Pro-arrhythmic and pro-ischaemic effects of inhaled anticholinergic medications

http://thorax.bmj.com/content/68/1/114.full?utm_content=HT_A6&utm_medium=Link6&utm_medium=email&utm_campaign=ATS&utm_campaign=Thorax_ATS&utm_source=landingpage&utm_source=marketing_email&keytype=ref&siteid=bmjjournals&utm_term=&ijkey=rx9mxHs129chk

Conclusions

The inhaled anticholinergic agents ipratropium and tiotropium have the potential to increase the risk of serious cardiovascular events, including mortality, when used in the treatment of COPD. 

The authors urge caution in prescribing inhaled anticholinergics for patients with pre-existing arrhythmias or cardiac disorders.

Blood fibrinogen as a biomarker of chronic obstructive pulmonary disease

http://thorax.bmj.com/content/68/7/670.full?utm_source=landingpage&utm_medium=Link4&utm_campaign=ATS&utm_source=marketing_email&utm_medium=email&utm_campaign=Thorax_ATS&utm_content=HT_A4&utm_term=


Conclusions Fibrinogen is likely to be a useful biomarker to stratify individuals with COPD into those with a high or low risk of future exacerbations and may identify those with a higher risk of mortality.

Efficacy of 13-valent polysaccharide conjugate vaccine (PCV13) against Pneumococcal Pneumonia in Adults

http://www.nejm.org/doi/full/10.1056/NEJMoa1408544

CONCLUSIONS

Among older adults, PCV13 was effective in preventing vaccine-type pneumococcal, bacteremic, and nonbacteremic community-acquired pneumonia and vaccine-type invasive pneumococcal disease but not in preventing community-acquired pneumonia from any cause. 

Actualización 2015 de la guía de asma GINA

The 2015 update of the Global Strategy for Asthma Management and Prevention incorporates new scientific information about asthma based on a review of recent scientific literature by an international panel of experts on the GINA Science Committee. It is the first annual update of the document since a major revision was launched on World Asthma Day, May 6, 2014. This comprehensive and practical resource about one of the most common chronic lung diseases worldwide contains extensive citations from the scientific literature and forms the basis for other GINA documents and programs.

http://www.ginasthma.org/documents/4

Toma de decisiones compartida y medicina mínimamente impertinente en pacientes con EPOC

Shared decision making and minimally disruptive medicine for COPD patients

http://minimallydisruptivemedicine.org/2015/04/08/shared-decision-making-and-minimally-disruptive-medicine-for-copd-patients/

Sobre la medicina mímimamente impertinente :

https://rafabravo.wordpress.com/2012/06/13/con-uds-victor-montori-y-la-medicina-minimamente-impertinente/