11 de marzo de 2015

Indacaterol/glicopirronio frente a Tiotropio/formoterol en EPOC moderada-grave : Estudio QUANTIFY


http://thorax.bmj.com/content/early/2015/02/12/thoraxjnl-2014-206345.full.pdf+html

Conclusions:
Indacaterol/glycopyrronium is non-inferior to TIO+FOR in improving HRQoL, with clinically meaningful and significant improvements in breathlessness and lung function in patients with COPD.

Azitromicina en infecciones respiratorias de vías bajas: una revisión Cochrane



http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD001954.pub4/abstract

Authors' conclusions

There is unclear evidence that azithromycin is superior to amoxycillin or amoxyclav in treating acute LRTI. In patients with acute bronchitis of a suspected bacterial cause, azithromycin tends to be more effective in terms of lower incidence of treatment failure and adverse events than amoxycillin or amoxyclav. However, most studies were of unclear methodological quality and had small sample sizes; future trials of high methodological quality and adequate sizes are needed.

Efecto de tiotropio sobre mortalidad

http://www.saludcastillayleon.es/portalmedicamento/es/cim-sacyl/ojo-markov/mortalidad-tiotropio-evidencias-discusion

Informe de Posicionamiento Terapéutico de indacaterol/ bromuro de glicopirronio de la AEMPS

http://www.aemps.gob.es/medicamentosUsoHumano/informesPublicos/docs/IPT-ultibro-breezhaler.pdf